Ronald M Evans Selected Research

Cytoplasmic and Nuclear Receptors (Nuclear Receptors)

12/2021	Colon cancer checks in when bile acids check out: the bile acid-nuclear receptor axis in colon cancer.
10/2019	RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype.
10/2019	The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease.
12/2016	Liver Cancer Checks in When Bile Acid Clocks Out.
1/2016	Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages.
5/2014	Nuclear receptors rock around the clock.
5/2013	PPARγ signaling and metabolism: the good, the bad and the future.
3/2013	Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice.
1/2012	Nuclear receptors as modulators of the tumor microenvironment.
5/2011	Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism.

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Ronald M Evans Research Topics

Disease

28	Neoplasms (Cancer) 01/2021 - 01/2002
27	Inflammation (Inflammations) 01/2022 - 10/2003
21	Insulin Resistance 01/2022 - 03/2003
20	Obesity 01/2022 - 04/2003
15	Type 2 Diabetes Mellitus (MODY) 01/2022 - 03/2003
11	Metabolic Diseases (Metabolic Disease) 01/2022 - 06/2003
11	Fibrosis (Cirrhosis) 01/2021 - 01/2012
10	Atherosclerosis 08/2014 - 10/2002
7	Pancreatic Neoplasms (Pancreatic Cancer) 12/2021 - 09/2014
6	Cholestasis 02/2015 - 02/2004
5	Non-alcoholic Fatty Liver Disease 01/2019 - 02/2016
5	Liver Diseases (Liver Disease) 01/2018 - 02/2005
5	Dyslipidemias (Dyslipidemia) 12/2017 - 12/2003
4	Fatty Liver 01/2021 - 09/2014
4	Autoimmune Diseases (Autoimmune Disease) 10/2019 - 12/2003
4	Carcinogenesis 01/2019 - 12/2014
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 07/2015
3	Colonic Neoplasms (Colon Cancer) 12/2021 - 05/2002
3	Breast Neoplasms (Breast Cancer) 10/2019 - 03/2004
3	Hyperglycemia 01/2019 - 02/2006
3	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 01/2002
3	Hepatocellular Carcinoma (Hepatoma) 11/2017 - 12/2014
3	Liver Cirrhosis (Hepatic Cirrhosis) 01/2015 - 05/2012
3	Glucose Intolerance 12/2011 - 12/2003
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2011 - 03/2006
3	Cardiomegaly (Heart Hypertrophy) 11/2007 - 11/2004
2	Weight Loss (Weight Reduction) 11/2021 - 03/2013
2	Multiple Sclerosis 10/2019 - 12/2003
2	Hyperlipidemias (Hyperlipidemia) 01/2019 - 06/2003
2	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2019 - 03/2004
2	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2017 - 03/2004
2	Adenocarcinoma 10/2017 - 04/2017
2	Disease Progression 12/2016 - 11/2013
2	Wounds and Injuries (Trauma) 01/2016 - 11/2012
2	Prostatic Neoplasms (Prostate Cancer) 01/2016 - 01/2016
2	Primary Myelofibrosis (Myelosclerosis) 08/2015 - 11/2013
2	Weight Gain 02/2015 - 09/2014
2	Pancreatitis 01/2015 - 09/2014
2	Starvation 10/2012 - 05/2012
2	Leukemia 09/2012 - 02/2006
2	Cardiomyopathies (Cardiomyopathy) 12/2011 - 11/2004
2	Shock 10/2011 - 09/2008
2	Bone Resorption 06/2010 - 12/2007
2	Heart Failure 07/2007 - 11/2004

Drug/Important Bio-Agent (IBA)

20	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 12/2021 - 05/2004
15	LigandsIBA 01/2015 - 03/2002
14	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 05/2004
13	PPAR gammaIBA 06/2010 - 10/2002
12	Insulin (Novolin)FDA Link 01/2017 - 03/2003
11	Bile Acids and Salts (Bile Acids)IBA 12/2021 - 02/2004
9	LipidsIBA 01/2021 - 10/2003
9	Fatty Acids (Saturated Fatty Acids)IBA 12/2017 - 06/2003
9	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 02/2016 - 06/2003
8	Proteins (Proteins, Gene)FDA Link 11/2021 - 02/2002
8	Pharmaceutical PreparationsIBA 01/2019 - 06/2003
8	PPAR deltaIBA 03/2008 - 01/2002
6	Hormones (Hormone)IBA 01/2022 - 03/2008
6	Calcitriol Receptors (Calcitriol Receptor)IBA 11/2020 - 04/2013
6	ThiazolidinedionesIBA 02/2016 - 12/2003
5	CholesterolIBA 10/2019 - 03/2002
4	CytokinesIBA 01/2022 - 09/2008
4	Vitamin D FDA LinkGeneric 11/2020 - 05/2002
4	GlucocorticoidsIBA 01/2019 - 10/2011
4	Co-Repressor ProteinsIBA 01/2017 - 05/2006
4	Triglycerides (Triacylglycerol)IBA 02/2015 - 02/2003
4	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 11/2013 - 03/2004
4	RetinoidsIBA 11/2013 - 03/2004
3	EnzymesIBA 01/2022 - 09/2013
3	LeptinIBA 01/2022 - 12/2003
3	DNA (Deoxyribonucleic Acid)IBA 11/2020 - 04/2017
3	Rosiglitazone (Avandia)FDA Link 01/2020 - 02/2010
3	fibroblast growth factor 21IBA 01/2019 - 10/2012
3	polyglutamineIBA 01/2019 - 03/2004
3	Fibroblast Growth Factor 1 (FGF-1)IBA 10/2017 - 09/2014
3	amlexanox (Aphthasol)FDA Link 07/2017 - 03/2013
3	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 01/2016 - 11/2013
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 05/2012
2	GlycogenIBA 11/2021 - 09/2014
2	CollagenIBA 11/2020 - 08/2015
2	ChromatinIBA 11/2020 - 10/2020
2	MethyltransferasesIBA 10/2020 - 04/2017
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2018 - 01/2015
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2017 - 10/2017
2	AntigensIBA 11/2017 - 12/2003
2	Phosphotransferases (Kinase)IBA 07/2017 - 03/2013
2	Histones (Histone)IBA 01/2017 - 08/2014
2	Androgen Receptors (Androgen Receptor)IBA 01/2016 - 01/2016
2	calcipotriene (calcipotriol)FDA LinkGeneric 11/2015 - 09/2014
2	Biological ProductsIBA 11/2015 - 09/2013
2	Pregnane X ReceptorIBA 09/2013 - 07/2006
2	Orphan Nuclear ReceptorsIBA 05/2013 - 05/2006
2	SteroidsIBA 05/2013 - 03/2011
2	CorticosteroneIBA 05/2013 - 12/2011
2	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 10/2011 - 09/2008
2	Transcription Factors (Transcription Factor)IBA 10/2011 - 05/2011
2	PPAR alphaIBA 03/2006 - 05/2004

Therapy/Procedure

22	Therapeutics 12/2021 - 03/2002
3	Drug Therapy (Chemotherapy) 01/2019 - 05/2011
2	Castration 01/2016 - 01/2016
2	Ligation 05/2012 - 02/2005